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1st Floor, Saudi Pak Tower, Islamabad


Understanding Infertility

Problems of infertility exist from times immemorial. Issues relating to human infertility have a profound impact on society. There is a range of emotions that people feel when their expectations and beliefs are challenged by problems in achieving reproduction. The couple may feel low self esteem, loss of self confidence, feeling of incompetence, a feeling of failure, a feeling of worthlessness, a feeling of outcast, isolation, loneliness, guilt, blame, fear, anger, shame, bitterness and frustration. Treatment is a genuine option.

On the average it takes one year for 80% of the couples to succeed in achieving pregnancy. It would take another one year for 10% of the original 100% couples to be successful. At the end of two years, the remaining 10% of couples would require some sort of help to achieve pregnancy. The aim of this clinic is to Help the remaining 10% unfortunate couples who fail to achieve a successful outcome after two years of effort.

Fertilization requires successful union of oocytes (eggs) from females and sperm from male. This union takes place in the far end of Fallopian tubes (the passage for travel of eggs, sperm and embryo extending from the uterus reaching the ovaries). Fertilization results in embryo formation which then slowly travels towards the womb and six days later reaches its final destination to get attached to the lining of the womb. Once this attachment is successful, pregnancy results and embryo slowly grows into fetus, which at an opportune time is delivered resulting in a baby.

For successful fertilization and implantation to occur it is important that egg and sperm are available at the right time, the passage for the travel of sperm and later embryo is available and finally the lining of the womb should welcome the newly formed embryo.

Of the 10% couples who need our assistance, half have problems relating to the production of adequate sperm. The normal sperm count is between 20 – 120 million/ml. Out of these, more than 50% should be actively motile. Males with sperm count lower than this would need some sort of assistance. If the count is borderline and majority of sperm are motile, then the quality of the semen sample can be improved by different laboratory techniques, so that this laboratory purified sperm sample can be placed in the womb by a very simple procedure called IUI (Intra-Uterine Insemination). For more severe deficiency in quality or quantity of sperm production individual sperm can be injected into individual eggs by a very elaborate laboratory technique called ICSI (Intra-Cytoplasmic Sperm Injection). If the sperm production is zero or the passage of sperm from testis to urethra is damaged or due to some other problem ejaculation is not possible, then sperm can be retrieved surgically and individual sperm can be used for fertilization by ICSI. In 3% of males, there would be no sperm production because of the lack of machinery in the testis. By taking a suitable testicular sample, if immature sperm production is seen, then that immature sperm (spermatid) can also be micro-injected into the egg to achieve successful fertilization.

In females, under the age of forty, the most important cause of infertility is the blockage of passage where egg and sperm meet. At times this can be surgically corrected, however at other times, the passage is so much damaged that surgery is not a possibility. Eggs can then be collected by a simple procedure and mixed with the husband’s sperm in the test tube (hence the name, test tube baby). Once fertilization is seen in the laboratory, successful embryos are then put back in the womb just like in IUI or ICSI. This procedure bypasses the damaged passage and is called IVF (In-Vitro Fertilization).

IVF provides an opportunity to physically see under the microscope, the quality of eggs, sperm and whether fertilization has actually taken place. This procedure is not only curative but also provides a very important diagnostic tool to find the cause of infertility.

This clinic is equipped with all the diagnostic tools required to assess the cause of infertility and provides all the solutions available in the most advanced clinics in the world.

ICSI clinics are equipped with all the diagnostic tools required to assess the cause of infertility and provide all the solutions available in the most advanced clinics in the world. ICSI has two fully operational centers, one at Saudi Pak Tower Islamabad, the other at City Hospital Multan. The clinics have excellent facilities including their own fully equipped operation theaters, laboratories, ultrasound facility, consultation and counseling rooms, and a pleasant waiting area where patients and their attendants can relax over a cup of tea or coffee while awaiting their turn, or for reports.

Treatments offered at our clinics are :

  • Controlled Ovarian Stimulation (COS)
  • Intra Uterine Insemibation (IUI)
  • In Vitro Fertility (IVF)
  • Intra Cytoplasmic Sperm Injection (ICSI)
  • Spermatic Micro Injection (SMI)
  • Assisted Hatching (AH)

For the details of each of the above procedures please see next section Lab Excellence.